November 29th Conference Pearls

Dialysis Emergencies (Dr. Gruber):

  • Ask patient when last dialyzed
  • Ask patient about their dry weight
  • Ask patient if they still make urine
  • What are the different types of access?
    • Graft
      • Can use after 3 weeks
      • Need to avoid BP cuffs, circumferential bandages –> restrict flow –> thrombosis
    • Catheters (tunneled or un-tunneled)
      • High rate of thrombosis
    • Fistula
      • Increases pressure in walls of vein –> vein enlarges and walls thicken –>  allows vein to take repeated sticks
      • Requires 3-4 months before able to use; Longest functional use
  • Morbidity of ESRD:
    • Cardiovascular disease: 50%
      • If coding a renal patient, ask what is wrong with the heart?
      • Take any complaints of chest pain very seriously (they can have more symptoms with less ischemic disease than other patients)
    • Infection: 20%
    • Neurological: 6%
    • 4x mortality if:
      • Receive <4hrs week of dialysis
      • If start dialysis >60 y/o
  • What do I do with elevated troponins if their troponins are always elevated?
    • Get serial troponins (usually >20% serial change is threshold)
  • What do I do with acute volume overload in dialysis patients?
    • MC etiology: missed HD, diet
    • Ask about their dry weight and last dialysis session
    • Treatment similar:
      • IV Nitroglycerin
      • IV Lasix (60-100mg) – even if they don’t make urine
      • BiPAP
      • Hemodialysis
  • If patient is hypotensive, don’t forget to look for pericardial tamponade!
    • Right atrial diastolic collapse- most specific sign
    • Easy to miss on CXR with cardiomegaly
    • 50% patients on dialysis have pericardial effusion (dialysis related or uremic related)
    • If pericardial effusion and hypotensive:
      • 1st step – IVF (increase venous return as these patients are preload dependent)
      • Then, can do an ultrasound guided pericardiocentesis
  • If patient is bradycardic, think about Hyperkalemia!
    • K+ number does not correlate to EKG changes
    • Often require 3 rounds of calcium gluconate to see EKG changes resolve
    • Use half dose of insulin in ESRD patients (insulin is excreted by kidneys so stays around longer)
      • Do not give albuterol as the first and only medication
  • What do I need to remember for a septic ESRD patient?
    • #1 source = catheters
    • Broad spectrum antibiotics to cover MRSA and pseudomonas
    • Give 250cc fluid bolus and re-evaluate
    • Talk to renal about whether catheter needs to be pulled
  • Why do patients become hypotensive during dialysis?
    • Inadequate time for transcellular shifts
    • May require longer or more frequent dialysis sessions instead
    • Autonomic dysfunction
    • It is an independent predictor of mortality
  • What are the neurological complications in ESRD patients?
    • CVA (2/2 poor protoplasm and HTN)
    • More likely hemorrhagic 2/2 platelet and clotting dysfunction
      • Intracranial bleed: 10x higher and 40% mortality
    • Encephalopathy (2/2 uremia or HTN or dialysis disequilibrium syndrome)
    • Seizures
      • 1/2 your dose of Phenytoin since most ESRD patients have hypoalbuminemia leading to displacement of drug from serum proteins –> increase in volume of distribution –> same pharmacologic effect with lower total blood concentration (level that you check in the blood)
    • Dialysis disequilibrium syndrome
      • 2/2 rapid changes in body fluid composition and osmolality
      • Usually when you start dialysis
      • Sx: HA, malaise, N/V, cramps to AMS, seizure or coma
      • Sx can resolve spontaneously over hours (as fluid/solutes redistribute)
      • Tx: lower ICP with mannitol or hypertonic NS
  • Vascular Access Problems
    • AV Fistula Stenosis: from endothelial/fibromuscular hyperplasia
      • Inflow Stenosis
        • Weakened radial pulse
        • High pitched bruit at site of stenosis
      • Outflow Stenosis
        • Bounding pulse distal to stenosis
        • Loss of thrill
    • Thrombosis
      • MCC: stenosis –> decreased blood flow/increased venous resistance
      • Can occur after HD from low BP (venous stasis) and excessive compression of access site for hemostasis post dialysis
    • Aneurysm/Pseudo-aneurysm:
      • From excessive cannulation –> weakening of vessel wall
      • Can present with pain or neurologic complaints (2/2 compression of nerves)
      • Pseudo-aneurysm: pulsating extravascular hematoma
      • Use ultrasound and obtain a Vascular consult
    • Bleeding
      • Why?
        • Inherent anticoagulation 2/2 uremia and platelet dysfunction
        • Also given heparin to prevent clotting in the dialysis circuit
      • Stop with direct pressure/elevation and surgical
      • 2 hand method: Dominant hand applying direct pressure to bleeding site/distal to the site while non-dominant hand applying pressure proximal to bleeding site
      • Figure of 8 stitch
      • Worst case scenario: tourniquet proximal to puncture site (but will cause thrombosis)
      • Consider protamine sulfate (if within hours of dialysis to reverse heparin)
        • Give slowly (can cause histamine reaction and anaphylaxis)
      • Consider DDAVT (releases vWF)
        • Do not give in hyponatremia, CHF or unstable angina
      • Consider TXA
      • Consider FFP/Cryoprecipitate
      • Observe for 2 hours for rebleed or thrombosis
      • Check thrill and listen for bruit prior to d/c

Serving Deaf in Medical Settings (Kerrie Ellen):

  • Watch Video
  • “The single biggest problem with communication is the illusion that is has taken place.” -G.B. Shaw
  • Deaf culture and their visual approach to the world may make them seem not with it, distracted, or spastic.
  • Not all Deaf can read your lips. Can you read their lips? Are you sure?
  • Written communication might work, but it might lead to misinformation and missed information.
  • Be careful using VRI (Video Remote Interpreter, or the machine interpreter)- it doesn’t facilitate communication for everyone all the time.
  • Using a family member as an interpreter is tricky since less than 10% of hearing family members can communicate effectively with the Deaf
  • Basic Sign Language you can use while waiting for your interpreter
  • To request interpreter during business hours at Jacobi, call ex. 5245 (talk to Maja)

Priapism (Dr. Ndukwe):

  • For penile blocks, aspiration and phenylephrine injections…aim for 10 o’clock or 2 o’clock on dorsal aspect.
  • Ventral approach risks hitting urethral and dorsal midline approach risks hitting penile vasculature
  • Get a thorough history (if possible, obtain medication list)
  • Do a thorough physical exam (e.g. lower leg weakness + priapism = spinal cord pathology)
  • Give IM terbutaline +/- PO ephedrine from the get go (Anecdotally, Gruber said this has worked for many of his priapism cases)

Hands-on Defibrillation (Dr. Schramm):

  • Reducing CPR interruptions = better short/long-term pt outcomes
    • With every pause in CPR, coronary perfusion pressure rapidly drops
    • Perfusion pressure is not quickly restored once CPR resumes (takes time to come back up)
    • Good evidence that maintaining coronary perfusion pressures leads to improved likelihood of ROSC.
  • No evidence yet that hands-on defibrillation (should minimize loss of
    perfusion pressure) improves outcomes

    • That being said…research lags because there aren’t enough people willing to perform it…because we’re afraid of getting electrocuted
  • Where does a defibrillation shock go?
    • Voltage path: from anterior/superior pad –> lateral/posterior pad
    • Nearly all voltage passes along the direct route, except for a small amount of voltage leakage
    • Defibrillation shocks do not travel to the patient’s feet, stretcher, air around the stretcher, or into your hands.
  • How dangerous is hands on-defibrillation?
    • No evidence of any provider ever going into V-fib after an accidental shock.
    • Much anecdotal data suggests safe using regular exam gloves.
    • However…
      • Insensible levels of voltage exposure are theoretically cardio-active (dangerous)
      • Regular exam gloves probably break down with repeated shocks and may not provide sufficient protection.
    • Rubber class 1/0 high-voltage, electrical gloves protect against direct voltages vastly higher than experienced by a CPR provider.
  • Proposition:
    • We do potentially dangerous procedures all the time (IV/central line placement, code panda, chest tubes on pts receiving CPR)
      • Each of these is more likely to injure the provider, than hands-on-defib.
    • We probably should not change our practice right away, at least not at an institutional level.
    • Don’t be needlessly scared of the defibrillator!
    • Attempt to minimize CPR interruptions!

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